Uji Efektivitas Teh Kombinasi Rimpang (Jahe, Lengkuas, dan Kunyit) terhadap Penurunan Kadar Gula Darah Mencit Putih Jantan  (Mus musculus) yang Diinduksi dengan Aloksan secara In Vivo

Hastrina Novasari; Anisa Febriyana

doi:10.62027/vitamedica.v4i3.1103

Authors

Hastrina Novasari Universitas Imelda Medan
Anisa Febriyana Universitas Imelda Medan

DOI:

https://doi.org/10.62027/vitamedica.v4i3.1103

Keywords:

Blended Tea, Blood Sugar Levels, Galangal, Ginger, Turmeric

Abstract

Diabetes mellitus is a metabolic disorder characterized by elevated blood glucose levels due to impaired insulin secretion or action. Long-term use of synthetic antidiabetic drugs has the potential to cause side effects, making natural treatment alternatives necessary. A combination of ginger, galangal, and turmeric rhizomes contains secondary metabolites that may help lower blood glucose levels. To determine the effectiveness of a tea made from a combination of ginger, galangal, and turmeric rhizomes in lowering blood glucose levels in male white mice with alloxan-induced diabetes and to identify the most effective dose. This in vivo experimental study used 30 male white mice divided into six groups: K, KN, KP, K1, K2, and K3. Blood glucose levels were measured on days 0, 3, 7, and 14, then analyzed using a one-way ANOVA followed by an LSD test. Administration of the tea blend of ginger, galangal, and turmeric significantly reduced blood glucose levels (p < 0.05). On day 14, blood glucose levels decreased to 91.25 mg/dL in group K3, 108.25 mg/dL in group KP, and 88.25 mg/dL in group K; the blood glucose level in group K3 was lower than that in group KP and approached that of group K. The tea blend of ginger, galangal, and turmeric rhizomes was effective in lowering blood glucose levels at a dose of 600 mg/kg body weight, which was found to be the most effective dose.

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